playMichael F. FlorioNov 15, 2026, 07:00 AM ETCloseMichael F. Florio is a fantasy football writer and analyst for ESPN Fantasy. He is an analyst on NFL Network’s NFL Fantasy Live and frequent guest on other network shows.
He has been a fantasy football analyst for the last 15 years, with his work featured at a number of publications, and is an FSWA award winner.Multiple AuthorsOpen Extended ReactionsBiggest injury concerns for Week 10Players in GermanyAmon-Ra St. Brown, WR, Lions (ribs): The “Sun God” was limited at practice this week and is listed as questionable but appears to be likely to play in Week 10. He played through the injury last week and surpassed 16 fantasy points. St.
Brown, who is a German citizen, will look to put on a show.A.J. Brown, WR, Patriots (ankle/knee): Brown has been limited at practice this week and was listed as questionable headed into Sunday’s game. However, he is currently expected to play. Brown averaged eight targets per game for the two times that he played on over 75% of snaps.
Given all the missed time, he brings some risk. Still, fantasy managers should probably take the chance here as Brown has a fantastic matchup against the Lions, who have allowed the fourth-most WR fantasy PPG.Rhamondre Stevenson, RB, Patriots (knee): Stevenson was able to return in a limited fashion after missing practice to start the week. He is listed as questionable for Sunday, but is expected to play. He has a tough matchup against the Lions, who have allowed the second-fewest fantasy PPG.
They rank bottom six in rushing touchdowns and rushing yards per game allowed to RBs. Assuming he suits up, he’s a risky flex option.Hunter Henry, TE, Patriots (foot): Henry has been limited at practice this week but does not currently carry an injury designation for Week 10. That means he is expected to play. Henry is a TE1 worth starting against the Lions, who have allowed the most yards, touchdowns and fantasy points to tight ends.Don’t forget to check these out: Mike Clay’s Playbook | Week 10 Buzz Week 10 Rankings | Matchup rankings for Week 10Official Sunday inactives should begin coming in approximately 90 minutes before the scheduled kickoff times: around 11:30 a.m.
ET for the early games and 2:30 p.m. ET for the late-afternoon games.Refresh often for the latest information.Players with early startsHarold Fannin Jr., TE, Browns (groin): While Fannin was limited at practice this week, he has been removed from Cleveland’s injury report and will play in Week 10. The Texans’ defense is tough on tight ends, having allowed the fourth-fewest fantasy PPG to the position. Still, consider Fannin to be a TE1 this week in a game where the Browns might be trailing and needing to throw.Denzel Boston, WR, Browns (toe): Boston missed practice on Thursday before returning Friday.
He is questionable for Week 10, but HC Todd Monken said on Friday that Boston is “trending in the right direction.” On paper, Boston has a favorable matchup against the Texans, although they have been tougher as of late. He is in the WR3/flex range. If he were to sit, KC Concepcion gets the biggest boost and would be in a similar range as Boston. Fannin, albeit in a tough matchup, would also likely see a few more targets.Bhayshul Tuten, RB, Jaguars (ankle/foot): Despite missing practice this week, Tuten is off the practice report and will play in Week 10.
Tuten should be started in fantasy this week. The lone concern is the potential for him to see a reduced workload (just like last week). That would especially be the case if the Jaguars pull ahead, which is very likely against the Titans.Jakobi Meyers, WR, Jaguars (ankle): Meyers returned to practice Thursday and is off the injury report, meaning he will play in Week 10. Meyers has played through a number of injuries this season.
He is a flex option for those in deeper leagues. The Titans have allowed the most WR fantasy PPG and allow explosive pass plays at the third-highest rate.Jordan Addison, WR, VIkings (thumb): Addison hurt his thumb in practice on Friday and was listed as questionable for Week 10. He is considered to be a game-time decision. The team did elevate WR Jeshaun Jones from the practice squad, so its clear that there is some concern here.Garrett Wilson, WR, Jets (concussion): After sitting out Week 9, Wilson was limited at practice this week, but has reportedly cleared the league’s concussion protocol and will play in Week 10.
Fantasy managers should start him as a WR2. While he has been up and down, the Bills are allowing the 10th-most WR fantasy PPG. Plus, the Jets are likely to be playing from behind in this one and, thus, will have to throw.Omar Cooper Jr., WR, Jets (ankle): Cooper was limited at practice this week before upgrading to full on Friday. He is questionable for Week 10.
If Cooper plays, he’d be in the WR3 range but with much more upside. Cooper saw 11 targets last week and has surpassed 13 fantasy points in three of his past four games, including two 22-point efforts. Plus, Geno Smith should be very effective airing the ball out against a Bills secondary that has been very leaky at times. Adonai Mitchell (knee) popped onto the injury report Friday and is also questionable for the Jets.Travis Etienne Jr, WR, Saints (hamstring): Etienne, who has not played since Week 3, was limited at practice this week before upgrading to full participation Friday.
He has been activated off the IR and is expected to play in Week 10, per Adam Schefter. Do not be surprised if he has a reduced workload in his first game back. Even so, he would be in the RB2 range against the Panthers, who rank top-two in terms of the most rushing TDs and fantasy RB PPG allowed. Audric Estime, who was a popular streaming option can be benched if Etienne plays.Players with late startsBam Knight, RB, Cardinals (concussion): Knight has cleared the league’s concussion protocol and will play in Week 10.
Expect him to handle the bulk of early-down opportunities. Tyler Allgeier is the preferred fantasy play because he handles passing downs on a team that will likely throw often. Still, both are just flex options. Trey McBride is the only Cardinal who should be started this week.George Pickens, WR, Cowboys (hamstring): Pickens has been limited at practice but was removed from the injury report, meaning he will play Sunday.
Even though he has not duplicated his success from last season, Pickens is still good enough that when he plays, you start him in fantasy. If he were to sit, Ryan Flournoy becomes a streaming option in what could be a high-scoring game against the 49ers.Deebo Samuel Sr., WR, 49ers (hamstring): Samuel has practiced in a limited fashion this week and has been removed from the injury report, meaning he will play in Week 10. He is a WR3/flex play with upside against the Cowboys, who have allowed the seventh-most WR fantasy PPG. The 49ers will be without Mike Evans this week but did add Keenan Allen at the trade deadline.
Expect Allen to be used only in a limited fashion for his first game with a new team.Drew Lock, QB, Seahawks (right elbow/oblique): Lock had been limited at practice this week but has since been removed from the injury report, meaning he will play in Week 10. He’s a streaming option for those in need of a bye week/injury replacement. He faces the Raiders, who have allowed the most passing touchdowns and third-most QB fantasy PPG.Players on Sunday nightNo fantasy relevant injuries of note.Players on Monday nightLadd McConkey, WR, Chargers (back spasms): Twice in the past five weeks, McConkey has been active for his game but did not play a single snap. Last week, fantasy managers did not know he would not be playing until after kickoff.
This week, he is listed as questionable. Simply put, it’s very tough to trust him — especially since McConkey did not practice to start the week and this game is on Monday night. Sitting all your Chargers is probably the way to go.Ruled out before SundayMichael
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